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Santo Spirito Hospital
The Ospedale di Santo Spirito in Saxia is Europe's oldest hospital, boasting a history that spans over a thousand years. It was originally founded in the 8th century by King Ina of Wessex as a hostel for Anglo-Saxon pilgrims. In the 12th century, Pope Innocent III expanded the facility into a state-of-the-art hospital and entrusted its management to the Order of the Holy Spirit. The current monumental complex largely dates from the reign of Pope Sixtus IV, who oversaw its Renaissance reconstruction between 1471 and 1478. A highlight of the complex is the 'Corsia Sistina,' a grand ward measuring over 120 meters in length, adorned with magnificent frescoes depicting the life of Sixtus IV and the hospital's founding. The building also houses a precious historical library and a museum of medical history. To this day, parts of the complex continue to function as a medical facility, standing as an exceptional example of the intersection of architecture, art, and Christian charity.
- Location: Vatican
- Top sights: Ponte Vittorio Emanuele Secondo · Ponte Neroniano · Oratorio di Santa Maria Annunziata
Best time to visit & climate
The most pleasant time to visit is May, Jun, Sep.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg °C | 7 | 8 | 10 | 14 | 18 | 23 | 26 | 26 | 21 | 17 | 12 | 8 |
| Rain mm | 73 | 77 | 69 | 56 | 57 | 34 | 26 | 26 | 70 | 82 | 114 | 92 |
📋 Practical info
Geography
Facts
- Founded by King Ina of Wessex around the year 727.
- Reconstruction by Sixtus IV began in 1471.
- The Corsia Sistina ward is 120 meters long and 12 meters wide.
- Houses the Biblioteca Lancisiana with 19,000 volumes.
- The famous 'foundling wheel' was established in 1198.
- The building features a distinctive octagonal lantern tower.
Explore nearby
Notable places around
Route planner — Car & Motorhome
Where do you start? We build the route here, with stops and country notes along the way.
© OpenStreetMap contributors · OpenRouteService
Sights in the town Santo Spirito Hospital (10)
Ponte Principe Amedeo
A bridge in Rome, named after Prince Amedeo.
Auditorium Conciliazione
A building in Rome used for concerts and events.
Baailica di San Giovanni dei Fiorentini
A church in Rome, dedicated to John the Baptist.
Arco dei Banchi
An arch in Rome, part of the historic banking district.
Porta Santo Spirito
A gate of the Leonine walls in Rome, Italy.
Ponte Sant'Angelo
A bridge in Rome, built under Emperor Hadrian.
Sights nearby
Frequently asked questions
Is the Santo Spirito Hospital still in operation?
Who founded the hospital?
What is the 'Ruota degli Esposti'?
Where is the hospital located?
Can you visit the building?
Santo Spirito Hospital: where is it located?
Santo Spirito Hospital: what is there to see?
Santo Spirito Hospital: when is the best time to visit?
Santo Spirito Hospital: why is it worth visiting?

















